List of projects by field of study



Below you see a list of researchprojects within a certain field of study. Please use the selectbox to view researchprojects of another field of research.

It  is also possible to search for keywords.

Click the title of a researchproject for more details.

 

Application of Next-Generation Sequencing in managing hospital outbreaks with Multidrug Resistant Gram-Negative Bacteria

Researchers
Prof. dr. A.W. Friedrich

Keywords:
molecular biology molecular microbiology

Autophagy as target to reduce sterile inflammation: a potential treatment for auto-immune diseases.

Researchers
prof. F.G.M. Kroese
prof. A. Vissink
prof. H. Bootsma

Keywords:
immunology Autophagy animal models

C/EBPβ-LIP induced cancer cell metabolism

Researchers
Prof. dr. C.F. Calkhoven
T. Ackermann

Keywords:
Cancer cell metabolism nutrient addiction

Calorie mimetic activities of amino acids through regulation of C/EBPβ-LIP translation.

Researchers
Prof. dr. C.F. Calkhoven
M.A. Zaini

Keywords:
cancer metabolism Calorie restriction

Controlling immune cells in the degenerative brain in vivo

Researchers
Dr. T.J. van Ham

Keywords:
imaging neurodegeneration Microglia

Correlation of clinical characteristics and treatment outcome with genetic alterations (EGFR, KRAS, ALK, BRAF, ROS1 and p53) in NSCLC stage IV.

Researchers
Prof. dr. F. Griesinger

Keywords:
lung cancer molecular biology

DNA template strand analysis in single cells

Researchers
Prof. dr. P.M. Lansdorp
dr. D.C.J. Spierings

Keywords:
genomic instability sister chromatid exchanges chromatid segregation

Endothelial-Mesenchymal Transition in Cardiovascular Disease

Researchers
dr. G. Krenning
dr. J.A.J. Moonen

Keywords:
microRNA epigenetics signal transduction

Epigenetics of Endothelial Dysfunction

Researchers
dr. G. Krenning
Dr. M.C. Harmsen
M. Maleszewska

Keywords:
epigenetics Endothelial Cell Polycomb

Functional characterization of genetic susceptibility variants of Celiac disease

Researchers
V. Kumar
dr. S. Withoff
prof. dr. C. Wijmenga

Keywords:
transcription factor celiac disease autoimmune disease EMSA ChIP assay

Genetics of asthma: the role of Protocadherin-1 in airway epithelial integrity and function.

Researchers
M.C. Nawijn

Keywords:
asthma functional genetics bronchial epithelium

Genome instability and neurodegeneration

Researchers
prof. dr. H.H. Kampinga
Dr. S. Bergink

Keywords:
neurodegeneration DNA damage

Identification and characterization of novel regulators of the mammalian target of rapamycin (mTOR) network

Researchers
prof. dr. K. Thedieck

Keywords:
proteomics Metabolic signaling systems biology

Identification of the gene regulatory processes underlying the pathophysiology of type 2 diabetes.

Researchers
dr. J.W. Jonker

Keywords:
gene regulation energy metabolism type 2 diabetes

Imaging of Cancer Cell Death: pre-clinical development of new probes for quantification of caspase-3 activity and PS exposure

Researchers
prof. dr. S. de Jong
dr. H.H. Boersma
dr. A. Rybczynska
prof. dr. R.A. Dierckx
Prof. dr. P.H. Elsinga

Keywords:
pre-clinical imaging cancer cell apoptosis kinetic modeling

Impact of the gut microbiota on the gastrointestinal complications of cystic fibrosis

Researchers
dr. J.W. Jonker

Keywords:
intestinal disease cystic fibrosis microbiota

Inducing regeneration through manipulation of Wnt signaling

Researchers
dr. P.M. Weissert
Prof. dr. E.V. Berezikov

Keywords:
stem cells regeneration Wnt signaling

Investigating the role of lincRNAs in autoimmune diseases

Researchers
dr. S. Withoff
V. Kumar
prof. dr. C. Wijmenga

Keywords:
RNA celiac disease autoimmune disease

microRNAs in Diabetic Retinopathy

Researchers
dr. G. Krenning
J.F. Friedrich

Keywords:
microRNA diabetes Endothelial Cell

Pathotyping of Streptococus pneumoniae to obtain a better insight in the invasive disease potential of strains.

Researchers
Dr. J.J.E. Bijlsma
K. Elberse

Keywords:
Streptococcus pneumoniae molecular typing genome analysis

Regulation of aging and age-related disease by transcription factors, chromatin states, and the epigenome

Researchers
dr. C.G. Riedel

Keywords:
epigenetics transcriptional regulation aging

Regulation of genome stability in stem cells

Researchers
Prof. dr. P.M. Lansdorp
dr. E.J. Uringa

Keywords:
telomere DNA repair and replication Sequencing

Role of Fibroblast growth factor 1 (FGF1) in the development en therapy of type 2 diabetes

Researchers
dr. J.W. Jonker

Keywords:
obesity energy metabolism type 2 diabetes

Role of the small heat shock protein HspB8 in protein folding diseases and implication in peripheral neuropathies

Researchers
prof. dr. H.H. Kampinga
dr. S. Carra

Keywords:
Axonal transport vesicular trafficking molecular chaperones protein aggregation Autophagy

Stem cells and oncogenesis in a novel model organism

Researchers
Prof. dr. E.V. Berezikov
dr. D. Olivieri

Keywords:
cancer stem cells DNA damage response

Stem cells in heart failure research: generating an in vitro disease model.

Researchers
M.F.G.A. Hoes

Keywords:
stem cells cardiac differentiation iPSC

The regulation of stem cell decisions in developing and ageing tissues.

Researchers
Dr. J.T.M.L. Paridaen

Keywords:
development Stem cell division zebrafish

Transcriptional regulation of CFTR gene expression

Researchers
dr. J.W. Jonker
prof. dr. H.J. Verkade

Keywords:
cystic fibrosis nuclear receptors transcriptional regulation

Unraveling disease mechanisms in Noordzeeziekte (progressive myoclonus epilepsy due to GOSR2 mutations)

Researchers
prof. dr. O.C.M. Sibon
prof. dr. M.A.J. de Koning-Tijssen
dr. T.J. de Koning
Dr. D.S. Verbeek
dr. A.J.A. van de Sluis

Keywords:
Noordzeeziekte basic research disease models

Unraveling the causative genes – and pathways - for autoimmune diseases

Researchers
V. Kumar
dr. S. Withoff
prof. dr. C. Wijmenga

Keywords:
pathway analysis celiac disease autoimmune disease gene enrichment T cell genes

Unraveling the genetic and biological pathways of spinocerebellar ataxia

Researchers
Dr. D.S. Verbeek

Keywords:
neurodegeneration exome sequencing human genetics

Using next generation sequencing to study Lynch Syndrome

Researchers
Prof. R.M.W. Hofstra

Keywords:
colorectal cancer HNPCC microsatellite instability mismatch repair

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Laatst gewijzigd: 13 maart 2013