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Project properties
Title | Is dynamic multi-phase CT imaging in cancer patients useful? |
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Keywords | Multi-phase CT liver metastases diagnostic importance |
Researchers |
Dr. D. Yakar Dr. T. Kwee |
Nature of the research | Retrospective evaluation |
Fields of study | surgery radiology internal medicine |
Research question / problem definition |
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1. To evaluate the clinical utility of multi-phase CT for tumour detection in cancer patients. 2. To investigate if the optimal detectability is different for e.g. breast cancer, melanoma, renal cell carcinoma, thyroid cancer, and neuroendocrine tumours. |
Workplan |
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This project is suited for a medical student in his/her senior Bachelor (2nd or 3rd year) or Master phase for a period of 3 (minimum) to 6 months. The final product will be a co-authored scientific article. Time schedule: part 1: familiarisation with the topic; part 2: data collection; part 3: data analysis and manuscript writing. During this research internship, there is also the possibility to accompany the radiologist/nuclear medicine physician with daily clinical activities and attend clinical meetings with other medical specialists. |
References |
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1.Utility of dual phase liver CT for metastatic melanoma staging and surveillance. Winkler N, Rezvani M, Heilbrun M, Shaaban A. Eur J Radiol. 2013 2. Liver metastases from melanoma: detection with multiphasic contrast-enhanced CT. Blake SP, Weisinger K, Atkins MB, Raptopoulos V. Radiology. 1999. 3. Hepatic metastases from breast carcinoma: comparison of non-contrast, arterial-dominant, and portal-dominant phase spiral CT. Zimmerman P, Lu DS, Yang LY, Chen S, Sayre J, Kadell B. J Comput Assist Tomogr. 2000 4. Comparison of unenhanced, hepatic arterial-dominant, and portal venous-dominant phase helical CT for the detection of liver metastases in women with breast carcinoma. Sheafor DH, Frederick MG, Paulson EK, Keogan MT, DeLong DM, Nelson RC. AJR Am J Roentgenol. 1999. 5. Multiphase contrast-enhanced helical CT of liver metastases from renal cell carcinoma. Raptopoulos VD, Blake SP, Weisinger K, Atkins MB, Keogan MT, Kruskal JB. Eur Radiol. 2001 |