Project details


Improving personalized treatment in oncology (IPTO). Effects of integrated oncological decision making

oncology shared decision making personalized treatment

dr. B.L. van Leeuwen
drs. H. van der Wal- Huisman
Vera Hanewinkel

Type of project:
Stage Wetenschap / Research project

Nature of the research:
Clinical trial

Fields of study:

Background / introduction
Currently, oncological treatment plans and decision-making are predominantly based on medical information following strict guidelines. Based on the conviction that oncological treatment plans can and should be more tailored to the individual, an outline for the Integrated Oncological Decision-making Model (IODM) has been developed. The IODM aims to individualize treatment decisions through the integration of patient’s health status and goals/preferences in formulating treatment decisions.
Research question / problem definition
The primary objective of the current study is to evaluate the effect of the IODM on personalized decision-making. We hypothesize that with the use of the IODM, decisions will
more often differ from the MDT recommendation based on guidelines/expertise, and that use
of the IODM intervention will lead to more personalized decisions for Dutch cancer patients.
This project integrates the IODM in gynecologic oncology and oncologic urology in two hospitals. Patients in the participating tumor boards included. Both quantitative data (clinical data, patient characteristics, patient reported outcomes) and qualitative data (audio tapes) will be collected during the patient's care trajectory. Analyzes will be performed on both cohorts in order to evaluate the effect of the IODM.
Kader Passende zorg, Zorginstituut Nederland. 28-06-2022

Festen S, Kok M, Hopstaken JS, et al. How to incorporate geriatric assessment in clinical decision making for older patients with cancer. An implementation study. J Geriatr Oncol. 2019;10(6):951-
959. doi:10.1016/j.jgo.2019.04.006

Festen S, van der Wal-Huisman H, van der Leest AHD, et al. The effect of treatment modifications by
an onco-geriatric MDT on one-year mortality, days spent at home and postoperative complications. J Geriatr Oncol. 2021;12(5):779-785. doi:10.1016/j.jgo.2020.12.003
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