Project details
Choose a field of study
allergology (9)
anesthesiology (31)
biomaterials (12)
cardiology (38)
cardiology and thoracic surgery (14)
cell biology (47)
child and adolescent psychiatry (1)
dentistry (4)
dermatology (11)
diabetes (8)
endocrinology (12)
ENT medicine (12)
epidemiology (55)
epidemiology and statistics (20)
gastroenterology (55)
general internal medicine (8)
genetics (42)
geriatrics (21)
GP medicine (42)
gynaecology (10)
haematology (25)
health psychology (17)
health sciences (22)
immunology (32)
intensive care (28)
internal medicine (37)
laboratory medicine (8)
mass spectrometry (3)
medical biology (18)
medical education (6)
medical physiology (10)
microbiology (23)
molecular biology (34)
molecular imaging (6)
movement sciences (15)
nephrology (40)
neurology (76)
neurosurgery (14)
nuclear medicine (20)
obstetrics (10)
obstetrics (4)
oncology (77)
ophthalmology (6)
orthopedics (18)
pathology (17)
Patient Related Research (10)
pediatrics (83)
pharmacology (28)
plastic surgery (5)
psychiatry (38)
pulmonology (42)
radiology (59)
radiotherapy (7)
rehabilitation (22)
reumatology (11)
Sociale Geneeskunde (14)
Sociale Psychiatrie (3)
sports medicine (5)
Stamcelbiologie (3)
Straling en Stresscelbiologie (1)
Stralingswetenschappen (3)
surgery (94)
traumatology (8)
tropical medicine (7)
urology (10)
vascular medicine (20)
virology (3)
or
Choose a keyword
(Epi)genetic epidemiology (1)
(medical)genetics (5)
5jaars overleving (1)
:psychosocial and lifestyle determinants (4)
aanhoudende lichamelijke klachten (ALK) (1)
abdomen (1)
access to medicine (1)
ACE-inhibitor (1)
Acetabular fracture (1)
Acetylcholine (1)
Achilles tendinopathy (1)
Achilles tendinopatie (1)
ACS-NSQIP surgical risk calculator (1)
activated clotting time (1)
Acute flaccid myelitis (1)
Acute gastroenteritis (1)
Acute Myeloid Leukemia (1)
acute myocardial infarction (2)
adpkd (3)
Advanced cell culture (1)
Advanced imaging (1)
Advanced Microscopy (2)
adverse side effects (1)
Advice (1)
Africa (2)
ageing (4)
ageing lungs (1)
Ageing, Nuclear Envelope, Nuclear Pore Complex (1)
aging (1)
airway epithelium (1)
Alcohol (3)
Allergen immunotherapy (1)
Allergic asthma (1)
Allergologie (1)
Allergy (1)
allogene stam cel transplantatie (2)
Allogeneic stem cell transplantation (1)
Amalgaam (2)
ambulance (1)
Anaphylaxis (1)
ANCA associated vasculitis (1)
anesthesia (5)
Anesthesiologie (1)
anesthesiology (2)
angiogenesis (1)
animal models (1)
Animal research (2)
ankylosing spondylitis (2)
antenatal care (1)
Anti-epileptics (1)
Antibiotic allergy (1)
antibiotics (3)
anticoagulants (2)
antidepressants (4)
Antimicrobial resistance (2)
Antimicrobial Stewardship (1)
anxiety (1)
Aorta (1)
aortic stenosis (1)
Apoptosis (1)
Appendicitis (2)
arrhythmia (1)
arterioveneuze fistel, dialyse shunt (1)
Artificial Intelligence (3)
Aspergillus fumigatus (1)
Assessment (1)
asthma (7)
Asthma genes (1)
astma (1)
asylum seekers (1)
Ataxia (2)
atherosclerosis (3)
Atrial fibrillation (3)
Attitude medisch specialisten (1)
audiology (1)
autism (1)
autoantibodies (1)
autoantigen (1)
autoimmune blistering diseases (1)
autoimmune disease (6)
autologous stem cell transplantation (1)
Autophagy (2)
Axonal transport (1)
Balance (1)
bariatric surgery (1)
basic research (2)
Behandeling/follow-up (1)
Beslissingsondersteuning (1)
beta cell destruction (1)
Big Data (2)
Bijnier (1)
bile (3)
bile ducts (1)
biliary atresia (4)
bilirubin (1)
bio-informatics (1)
biochemie (2)
biofilm (1)
bioinformatics (1)
biomarker (2)
biomarkers (9)
biomaterials (1)
biomedical technology (3)
biorhythm (1)
bipolar disorder (3)
bleeding (2)
blood flow autoregulation (1)
blood loss (1)
Blood pressure (2)
Blood pressure variability (1)
blood-brain barrier (1)
bloodpressure (1)
brain (3)
brain metastases (2)
Brain metastasis (1)
brain tumour (2)
BRCA1/2 (1)
Breast (a)symmetry (1)
Breast augmentation mammoplasty (2)
breast cancer (5)
breast conserving surgery (1)
Breast implants (1)
Breast symmetry (1)
bronchial epithelium (1)
built environment (1)
Buruli Ulcer (3)
Calorie restriction (1)
Calprotectin (2)
cancer (30)
cancer cell apoptosis (1)
Cancer cell metabolism (1)
cancer cells (1)
cancer patients (2)
cannabis (1)
carcinogenesis (1)
Cardiac Amyloidosis (2)
cardiac differentiation (1)
Cardiac function (1)
cardiac output (1)
cardiac surgery (1)
cardio-pulmonary toxicity (1)
cardiogenetics (2)
cardiology (10)
cardiometabolic health (1)
cardiopulmonary bypass (1)
Cardiovasculaire effecten (1)
cardiovascular (4)
cardiovascular disease (6)
cardiovascular risk (1)
cardiovascular risk management (1)
cardiovascular surgery (1)
Cardiovascular toxicity (2)
caries (1)
carriers (1)
cartilage (2)
Catheterization lab (1)
celiac disease (4)
cell biology (1)
cell cycle (2)
cell death (3)
cell saver (1)
cellbiology (1)
cellular interactions (1)
Central Sensitization (nociplasticity) (1)
cerebral palsy (1)
cervical radiculopathy (2)
Cervical spine (2)
CHARGE syndrome (2)
chemotaxis (1)
chemotherapy (5)
chest CT (1)
child (2)
Child development (1)
child outcome (2)
childbirth (1)
children (9)
ChIP assay (1)
cholangiocyte (1)
cholestasis (1)
cholesterol fluxes (1)
chromosome (1)
chronic depression (2)
chronic disease (2)
Chronic Kidney Disease (5)
chronic lung allograft dysfunction (1)
Chronic rhinosinusitis (1)
chronic ventilatory support (1)
Chronische pijn (2)
Circadian rhythmicity (1)
cirrhosis (2)
Clinical decision making (1)
clinical decision-making (1)
clinical diagnostics (4)
clinical epidemiology (1)
clinical genetics (1)
Clinical retrospective patient outcome study (1)
Clinical Severity Score (1)
co-morbidity (1)
coagulation (1)
coating (1)
coccygodynie (1)
cochlear implant users (1)
Cognition (1)
cognition and outcome (2)
cognitive decline (1)
cognitive function (3)
cognitive impairment (1)
cognitive testing (1)
collect clinical information (1)
Colon carcinoma (1)
colonisation (1)
colorectal cancer (2)
colorectal cancer, CEA value, CT-scan, follow up (1)
colorectal surgery (3)
comorbidity: anxiety, aggression, emotion regulation problems, depression (1)
compensatory movements (1)
competency development (1)
complement (3)
complex congenital heart disease (1)
compliance (1)
complications (4)
Comprehensice geriatric assessment (1)
computed tomography (CT) (3)
Congenital anomalies (1)
congenital heart disease (3)
connective tissue disease (1)
Constipation (1)
continue glucose monitoring (1)
contraction (1)
contrastmiddel (1)
COPD (14)
Coronair angiografie (1)
coronary arteries (1)
coronary artery bypass grafting (1)
Coronary Artery Disease (3)
cosmetic outcome (1)
costs (3)
cough (1)
COVID-19 (6)
craniopharyngioma (2)
Craniotomy (1)
Critically ill children (3)
Crohn's disease (2)
Crohn's disease (3)
Crohn's disease (1)
CT (1)
CT imaging (2)
CT-scan (1)
cystic fibrosis (4)
cytokines (1)
Damage (1)
database (3)
database registry (1)
Deep brain stimulation (DBS) (6)
deletion (2)
delirium (1)
delivery agent (1)
dementia (3)
dental erosion (1)
dental hygiene (1)
dentist (1)
Deprescribing (1)
depression (4)
Depression, (2)
Depression, translational neuroscience (1)
dermatology (3)
Descriptive and retrospective study with clinical results (1)
development (3)
Developmental coordination disorder (1)
developmental disorder (1)
developmental disorders (1)
Developmental Dysplasia of the Hip (DDH) (2)
developmental psychopathology (1)
Dexamethasone (1)
diabetes (3)
Diabetes mellitus (4)
diabetis (1)
diagnostic importance (1)
diagnostic test (1)
diagnostics (3)
dialysis (3)
Diaphragm paralysis (1)
Diet (2)
dilated cardiomyopathy (1)
disease activity (1)
disease models (1)
Disease modifying therapy (1)
DNA (1)
DNA damage (1)
DNA damage response (1)
DNA methylation signatures (1)
donor (1)
Drosophila (2)
drug delivery (1)
Drug Interactions (1)
dry eye (2)
duplication (1)
Dupuytren's disease (1)
Dupuytren's disease (1)
Dystonia (6)
e-health (5)
early detection (1)
early life experiences (1)
Early Onset Ataxia (2)
eating disorders (1)
echo duplex, diagnotische waarde (1)
echocardiography (2)
eco-anxiety (1)
Education (2)
EEG-EMG (1)
effects (1)
Ehealth (10)
Elder (1)
elderly (6)
elderly cancer patients (1)
elderly patients (2)
electroconvulsive therapy (1)
Electronic Nose (1)
EMG (2)
EMG-analysis (1)
emphysema (1)
EMSA (1)
enamel (1)
end-expiratory lung volume (1)
endocrine disrupting chemicals (1)
endocrine therapy (1)
endocrinology (1)
endometriosis (1)
Endophenotypes (1)
Endothelial Cell (2)
endothelial cells (1)
endoveneuze laser behandeling (1)
energy metabolism (3)
engineering (1)
enkelletsel (1)
eNose (1)
epidemiology (9)
epidermolysis bullosa (2)
epigenetics (4)
epithelial cells (1)
epithelial disorders (1)
ercp (1)
errors (1)
erythropoietin (1)
Esophageal cancer (1)
esophageal carcinoma (2)
Esophageal pressure (1)
esophagus surgery (2)
Essential tremor (3)
ESWL (2)
ethics (1)
evidence-based medicine (1)
EVLT (1)
Ex vivo lung perfussion (1)
exercise testing (1)
exercise therapy (1)
Exercise training (1)
Exergames (1)
exome sequencing (3)
Faecalibacterium prausnitzii (1)
familial hypercholesterolemia (1)
Family history (2)
Farmacologie (1)
farmacology (1)
fatigue (4)
fatty acids (1)
fatty liver disease (1)
FDG PET/CT (2)
fecal incontinence (1)
fertility (1)
fetal gender (1)
fibrosis (3)
filling (2)
First Episode Psychosis (2)
first trimester anomaly scan (1)
first trimester ultrasound (1)
fitness (1)
fluid administration, hemodynamic monitoring (1)
fluid management (1)
Fluorescence imaging (1)
fMRI (1)
fNIRS-monitoring (1)
foot ulcers (1)
frailty (3)
Frailty screening (2)
Function Endoscopic Sinus Surgery (1)
functional genetics (2)
functional somatic symptoms (1)
Functional stroke mimic (1)
functionele symptomen (1)
Fungal Infections (1)
fysiotherapie (1)
gait (1)
galectin-3 (1)
Galgangatresie (1)
game (1)
gangliosides (1)
GBA1-gene (1)
GECKO (1)
Gender (1)
gene enrichment (1)
gene expression (1)
gene regulation (1)
general movements (1)
general practice (3)
general practitioner (1)
genetic diseases (1)
Genetic sequencing (1)
genetic testing (1)
genetics (5)
genome analysis (1)
genomic instability (1)
genotype-phenotype correlation (1)
geriatric oncology (1)
geriatrics (2)
glaucoma (2)
Glioblastoma (1)
Gliomas (1)
global child health (1)
global health (2)
Glomerular filtration rate (1)
Glucocorticoids (1)
glucose homeostasis (1)
growth hormone deficiency (1)
Guidelines (2)
Guillain-Barré syndrome (1)
Gunanine Nucleotide Exchange Factor (1)
Gut Microbiota Composition (2)
gut-liver acis (1)
haemophilia (2)
hand (1)
Head and neck cancer (5)
Health care professionals (1)
Health care utilization (1)
health economics (3)
Health indicators (1)
Health literacy (1)
Health Related Quality of Life (1)
health-related quality of life (4)
healthcare education (1)
healthcare transformation (1)
hearing impairment (1)
hearing rehabilitation (1)
heart (14)
heart failure (7)
Heart rate variability (1)
heart transplantation (1)
heart valve replacement (1)
heat shock proteins (1)
Heel prick Screening (1)
hematology, cancer, critical care, outcome (3)
hematopoiesis (5)
hemodynamic monitoring (2)
hemodynamics (1)
hemostasis (2)
heparin induced thrombocytopenia (1)
hepatitis (2)
hepatocellular carcinoma (1)
hereditary cancer (1)
hereditary kidney disease (1)
HFOV (2)
Hibernation (4)
Hidradenitis suppurativa (1)
hip (1)
hip and knee prothesis (2)
Hip artroplasty (1)
Historical controls (1)
HIV (3)
Hodgkin lymphoma (2)
Home mechanical ventilation (3)
Honours education (1)
hormone receptors (1)
HPB surgery (1)
huisarts (1)
Huisartsgeneeskunde (1)
human genetics (1)
human hematopoietic stem cells (3)
Humeral Fractures (1)
hydrochlorothiazide (1)
hydrogen sulfide (1)
hymenoptera venom allergy (1)
hyperglycaemia (1)
Hyperkinetic movement disorders (2)
Hypertensie (1)
hypoglycemia (1)
hypophospatemic rickets (1)
hypoplastic left heart syndrome (1)
hypotension (1)
IBD (4)
IGF-1 (1)
image biomarker (2)
imaging (12)
imaging, biomarkers (1)
Immune checkpoint inhibitors (3)
immune response (1)
immune suppression (1)
Immune-related adverse events (1)
immunity (1)
immunology (10)
immunosuppression (1)
immunotherapy (4)
impact (1)
implant infection (2)
in vitro (1)
in vitro fertilization (1)
Inborn Error of Metabolism (1)
incidence (1)
incontinence (2)
individualised treatment (1)
infant (2)
infant assessment (2)
infant development (3)
Infant Stool Colour Card (1)
infection (3)
Infection and inflammation (1)
Infectious diseases (1)
Infective Endocarditis (1)
inflammation (5)
Inflammatory bowel disease (3)
Inflammatory rheumatic disease (3)
Informatie-uitwisseling (1)
Information technology (1)
Inguinal Hernia Surgery (1)
innovatie van zorg (2)
insulin (1)
insulitis (1)
Integrative care (1)
intellectual disability (1)
Intensive care (1)
interactie (1)
interprofessional education (1)
Interviews (1)
Interviewstudie (1)
intestinal disease (2)
intestinal disorder (1)
intestinal integrity (1)
intestinal transplantation (2)
Intestinal wall permeability (1)
intestine (1)
Intracraniele druk (1)
Intraoperative neurophysiology (1)
IONM (1)
iPSC (1)
iron deficiency (2)
ischemia (3)
ischemia-reperfusion injury (1)
ischemia/reperfusion injury (2)
ischemic stroke (2)
Isolation (1)
isotopes (1)
IVF (3)
jaundice (2)
joint (2)
Ki67 proliferation index (1)
kidney (6)
kidney disease (5)
Kidney Donation (3)
kidney transplantation (13)
kidneydonor (1)
Kindergeneeskunde (1)
kinetic modeling (1)
Klinische onderzoeksstage (1)
knockout mouse (1)
kwaliteit van leven (2)
kwaliteit van zorg (1)
laboratory animals (10)
language development (1)
language screening (1)
laparoscopy (1)
laryngectomy (3)
late effects of treatment (1)
Leadership (1)
learning curve sonologist (1)
learning organization (1)
leefstijl (1)
leukemia (3)
leukemic stem cells (2)
LifeLines (2)
lifestyle (4)
liposomes (1)
lipotoxicity (1)
liver (3)
liver cancer (1)
liver disease (5)
liver diseases (1)
liver failure (1)
liver fibrosis (1)
liver metastases (1)
liver resection (1)
liver transplantation (10)
livercirrhosis (1)
locally advanced rectal caner (1)
locomotion (1)
long-term survival (1)
longitudinal (1)
lumg transplantation (1)
lung (4)
lung cancer (5)
Lung function (1)
lung mechanics (2)
lung nodules (2)
lung recruitment (1)
lung transplantation (5)
lymphoma (2)
lynch syndrome (1)
machine learning (Matlab/Rstudio) (1)
machine perfusion (2)
major depressive disorder (1)
mass spectrometry (2)
mast cells (1)
mastocytosis (3)
measurement tool (1)
mechanical ventilation (10)
medical comorbidity (1)
medical device (4)
medical education (2)
medical imaging (8)
medically unexplained symptoms (2)
medication (3)
Medication reviews (1)
medication safety (1)
medication treatment (1)
medicine (1)
melanoma (5)
Meningioma (2)
meno-pauze (1)
mental retardation (1)
metabolic diseases (5)
Metabolic signaling (1)
metabolic syndrome (3)
metabolism (3)
metabolites (1)
metabool syndroom (3)
metformin (1)
method development (2)
microbiome (1)
microbiota (3)
microcephaly (1)
Microglia (1)
microRNA (2)
Minimally invasive parathyroidectomy (1)
mitochondria (1)
MitraClip (1)
Mobile electrocardiogram devices (1)
Mobility (1)
molecular biology (2)
molecular chaperones (1)
Molecular Fluorescence Guided Surgery (1)
molecular mechanisms (1)
molecular microbiology (1)
Molecular tumour board (1)
molecular typing (1)
Monoclonal antibodies (1)
monocytes (1)
mood disorders (1)
Motor development (2)
Mouse models (1)
movement disorders (3)
MRI (8)
MRI / CT (1)
MRI / magnetic resonance imaging (3)
MRI brain (1)
MRS (1)
mucosal melanoma (1)
mucus clearance (1)
multi-morbidity (1)
Multi-organ failure (1)
Multi-phase CT (1)
multidrug resistance (1)
Multimorbidity (3)
multiple myeloma (2)
multiple sclerosis (4)
Musculoskeletal pain (1)
Music (1)
music intervention (1)
music therapy (4)
mutations (2)
myelin (1)
myocardial infarction (2)
myoclonus (1)
myoclonus dystonia (1)
NASH (1)
nasopharyngeal carcinoma (1)
Necrotische Enterocolitis (1)
necrotising enterocolitis (1)
nefropathie (1)
neglected diseases (1)
Neglected Tropical Diseases (1)
neoadjuvant chemoradiotherapy (1)
neonatal hypoglycemia (1)
Neonatal hypoxic-ischaemic encephalopathy (1)
Neonatal outcome (1)
neonatale icterus (1)
neonates (2)
neonatology (1)
nephrology (2)
neuro-endocrine tumors (1)
neurobiology (1)
neurocognition (1)
neurodegeneration (4)
neurodegenerative diseases (3)
neurodevelopmental impairment (1)
neurodevelopmental outcome (1)
neuroendocrine tumor (1)
Neuroimaging (5)
neuroinflammation (1)
neurological development (1)
neurology (1)
neuromuscular blockade (1)
neuropathic pain (1)
neuropathy (1)
neuropsychiatric symptoms (1)
Neurosurgery (4)
neurotransmitters (1)
neutropenia (1)
new genes (1)
nier (1)
non-Hodgkin's disease (1)
Non-invasive ventilation (2)
Non-motor symptoms (2)
Noordzeeziekte (1)
Nuclear Medicine (1)
nuclear receptors (1)
nursing home (1)
Nursing home residentss (1)
nutrient addiction (1)
nutrition (8)
obesity (6)
Occupational exposures (1)
Occupational health (1)
Older adults (1)
oligodendrocytes (1)
oncological epidemiology (1)
oncology (6)
oncoplastic surgery (1)
ongeplande heropname (1)
online wearables (1)
opthalmologic problems (1)
organ preservation (3)
organ transplant (1)
organ transplantation (2)
orthopedics (3)
osteomyelitis (1)
otolaryngology (1)
Ouderen (1)
outcome (2)
outcome and cognition (1)
Outcome Assessment (1)
Outcome measurement (4)
Outcomes (2)
Outocome (1)
ovarian cancer (1)
Overactieve blaas (2)
overweight (2)
Overweight/obesity (1)
oxidative stress (2)
oxygenation (1)
pain (2)
Pain (Chronic) (1)
PALB2 mutation (1)
palliatief (1)
Palliatieve zorg (3)
palliative care (1)
pancreatic resection (1)
pancreatoduodenectomie (1)
paralysis (1)
parental support (1)
Parkinson disease (4)
Parkinson's disease (4)
Parkinson's disease (2)
Parkinson’s disease (1)
Parkinson's disease (4)
Participation restriction (1)
pathological complete response (1)
pathology (1)
pathway analysis (1)
Patiënt-gerichtheid (1)
patient centered care (1)
patient experiences (2)
Patient perspective (1)
patient related research (1)
patient satisfaction (1)
Patient-Reported-Outcomes (1)
PD-L1 immunohistochemistry (1)
pediatric cardiology (2)
Pediatric gastroenterology (1)
Pediatric rehabilitation (1)
pediatrics (6)
Percutane Nefro-Litholapaxy (2)
Percutaneous coronary intervention (PCI) (1)
Percutaneous intervention (2)
Peri-Acetabular Osteotomy (PAO) or Bernese/Ganz osteotomy (2)
perinatal care and psychiatry (1)
perineal wound healing (1)
periodontitis (1)
perioperative care (1)
Periprosthetic joint infection (1)
peritonitis (1)
Persistent somatic symptoms (1)
personal medicine (1)
personalized (1)
Personalized medicine (3)
personalized treatment (1)
PET (6)
pet scintigraphy (1)
PET-tracer (1)
Peyronie disease (1)
pharmacodynamics (1)
pharmacokinetics (1)
pharmacology (4)
Phelan-McDermid syndrome (1)
phenomenology (1)
phenotype-genotype study (1)
phenylketonuria (1)
photometry (1)
physical activity (3)
physical and mental functioning (1)
physical therapy (1)
physiology (2)
placenta (1)
plasmacytoma (1)
plastic surgery (1)
platelet (1)
polisomnography (1)
Polycomb (1)
polypharmacy (7)
population cohort study (1)
population screening (2)
portal hypertension (1)
Positron Emission Tomography (1)
Postgraduate Medical Education (2)
postoperative complications (2)
postoperative outcome (1)
postoperative pain (1)
posttraumatic (1)
postural control (1)
potassium (1)
pre-clinical imaging (1)
Precision medicine (1)
predictiemodel (1)
Predictiemodellen (1)
prediction (1)
prediction modeling (2)
pregnancy (8)
Prehabilitation (1)
Prematuren (1)
prenatal diagnosis (1)
prenatal diagnostics (2)
prenatal programming (1)
preservation fluids (1)
preterm (1)
preterm birth (1)
Prevalence of cancer (1)
prevention (3)
preventive cardiovascular medication (1)
primairy health care (1)
primary care (7)
primary care, gastro-enteritis, children, out-of-hours service, pediatrics. (2)
Primary Hyperparathyroidism (1)
probiotics (1)
Proefschrift (1)
prognosis (3)
Prolapse surgery (1)
proliferation (1)
Promoveren (1)
prospective cohort study (1)
prostate cancer (1)
Prosthetic Valve (1)
protein aggregation (1)
protein kinase inhibitors (1)
protein restoration therapy (1)
proteomics (3)
prothrombin complex concentrate (1)
PSMA PET/CT (1)
Psychiatric symptoms (1)
psychiatry (1)
psychiatry, high-field MRI (1)
psychological stress (1)
Psychology (1)
psychosis (1)
psychosocial (2)
psychosocial and lifestyle determinants (1)
psychotherapy (1)
Publiceren (1)
pulmonary embolism (1)
pulmonary hypertension (2)
pulmonary rehabilitaion (1)
Pulmonary rehabilitation (1)
QST (1)
qualitative research (3)
quality improvement (1)
quality of life (7)
quality of reduction (1)
Quantification (1)
quantitative sensory testing (1)
questionnaire (3)
questionnaire research (1)
Radiology (11)
radiotherapy (30)
Randomized comparative trial (1)
randomized controlled trial (1)
raynaud (1)
RCT (1)
real world dosing (1)
Recommendation (1)
recovery (1)
rectal cancer (2)
rectum carcinoma (1)
Recurrence (1)
referral (1)
refugees (1)
regeneration (3)
rehabilitation (5)
Relatives (1)
Renal cell carcinoma (1)
renal disease (2)
renal transplantation (1)
renal tubular epithelium (1)
reperfusion (2)
Reproducibility of Results (1)
reproductive health (1)
reproductive immunology (2)
respiratory failure (1)
respiratory viruses (2)
restoration (1)
retina (2)
retinal physiology (1)
retrospective (1)
revision surgery (1)
rheologic and oxygen transport capacity (1)
Right ventricular failure (1)
risk factors (2)
RNA (1)
Robot-assisted surgery (1)
ROC curve (1)
running (1)
Safety (1)
saliva (1)
SARS-CoV-2 vaccination (1)
Schildklierkanker (1)
schizophrenia (2)
screening (1)
Screening tools (3)
Seating devices (1)
Second opinion (1)
Selective Internal Radiotherapy (1)
Self - Determination Theory (1)
self-management (1)
self-renewal (2)
sensitisatie van het centraal zenuwstelsel (1)
Sentinel lymph node (1)
Sepsis (2)
Sequencing (1)
serious gaming (1)
severe mental disorders (1)
sex-specific (1)
shared decision making (3)
shear wave ultrasound (1)
signal transduction (1)
Single Nucleotide Polymorphisms (SNP) (1)
sinonasal (1)
siRNA (1)
Sjogren's syndrome (1)
Sjögren's syndrome (1)
skeletal muscle mass (1)
Skin cancer (3)
Sleep (1)
small for gestational age (1)
small molecular drugs (1)
Social media (1)
soft tissue sarcoma (2)
spataderen (1)
spectroscopy (1)
Spine surgery (1)
sport (1)
sport medicine (1)
sports injury (1)
Stage wetenschap / research project (1)
statistics (1)
steatosis hepatis (1)
Stem cell division (2)
stem cells (4)
stenose (1)
stoma (1)
Streptococcus pneumoniae (2)
stress (5)
stroke (2)
stuitpijn (1)
subarachnoid hemorrhage (1)
surgery (8)
surgery induced muscle loss (1)
surgical oncology (2)
surgical resection (1)
surgical treatment (1)
survey (2)
survival (2)
survival, Epstein-Barr virus (1)
Survivor care (3)
symptom perception (1)
synaptic density (1)
syndrome (1)
Systematic Review (3)
systemische sclerose (1)
systems biology (1)
T cell genes (1)
TARC (1)
target organ injury (1)
team (1)
teeth restoration (1)
teleconsultatie (1)
telemonitoring (1)
tendinopathy (1)
therapy compliance (1)
therapy resistance (1)
Thiosulphate sulfurtransferase activation (1)
thoracic endovascular aortic repair (1)
thoracic irradiation (1)
thrombolysis (1)
thrombosis (5)
Thyroid cancer (1)
thyroid gland (1)
time alignment (1)
TIPS (1)
TNF (1)
tolerance induction (1)
tolvaptan (1)
total hip arthroplasty (2)
total knee arthroplasty (1)
Toxicities (1)
Transanal TME (1)
transcatheter aortic valve implantation (1)
transcraniëel Doppler onderzoek (TCD) (1)
Transcranial Magnetic Stimulation (2)
transcription factor (1)
transcriptional regulation (2)
translation validation (1)
translational (4)
transplant rejection (1)
transplantatation (1)
Transplantatie (1)
transplantation (34)
transplantation medicine (1)
Transplantation surgery (1)
TransplantLines (2)
transport proteins (1)
Transpulmonary pressure (1)
traumachirurgie (1)
traumatic brain injury (3)
traumatisch hersenletsel (1)
Treatment (3)
Treatment goals (1)
Treatment response (1)
tremor (2)
tricyclic antidepressants (1)
triglyceride (1)
trombose (1)
tropical medicine (1)
TSST (1)
Tuberculosis (1)
type 2 diabetes (2)
tyrosinemia (1)
uitdroging (1)
uitkomst (1)
ulcerative colitis (5)
ultrasound (4)
upper extremity (2)
urinary tract infection (2)
Urolithiasis (3)
vaatmetingen (1)
vaccine (2)
Validation study (2)
value based healthcare (1)
vascular graft infection (1)
vascular medicine (4)
vascular surgery (3)
vasculitis (1)
Venous thromboembolisms (1)
venous thrombosis (4)
Ventilator induced lung injury (2)
Verteporfin (1)
vesicular trafficking (1)
vestibular dysfunction (1)
virology (1)
Virtual Reality (4)
virus (2)
visual field testing (1)
visual neuroscience (1)
vitamin D (1)
vitamin D deficiency (1)
vitamin K antagonists (1)
voetletsel (1)
volumetry (1)
Von Hippel-Lindau (1)
VTE (1)
waiting list (1)
walking (1)
Weaning (1)
Wegener's granulomatosis (1)
West Africa (1)
whole exome sequencing (1)
Wnt signaling (1)
Work capacity evaluation (1)
Work of breathing (1)
X-rays (1)
young patients (1)
zebrafish (2)
Zelfbeoordelingslijst (1)
zuurstofsaturatie (1)
Effective elements in consultations with children suffering from persistent somatic symptoms: a clinical cohort study
Keywords: pediatrics
prospective cohort study
Persistent somatic symptoms
Researchers:
Prof. dr. J.G.M. Rosmalen
Irma J. Bonvanie
Michel J. van Vliet
Arvid Kamps
Janneke van Leeuwen
Type of project: Stage Wetenschap / Researchproject
Nature of the research:
Clinical, prospective, observational research. We will extract data from medical files and obtain quantitative data from children and parents by questionnaires before and after consultation with a pediatrician.
Fields of study:
pediatrics
psychiatry
Background / introduction
Persistent somatic symptoms (PSS) are symptoms without a univocal biomedical diagnosis. PSS such as headache or fatigue are very common in children and can lead to substantial impairments. The cause of PSS is thought to be multifactorial with psychological, social and biological factors all playing a role. How the diagnosis of PSS is communicated with parents and children is expected to be very relevant for illness perception, acceptance, and (start with) recovery. Yet, surprisingly little is known about current practice of step one treatment in pediatric care, and the supposedly effective elements of this treatment. More insight into working elements of step one treatment can provide more specific evidence-based recommendations for practitioners in the treatment of pediatric patients with PSS. We therefore aim to perform a pilot of a clinical cohort study. The overall aim of the eventual cohort study is to identify the used, appreciated, and working elements in consultations of pediatricians with children and their parents suffering from PSS. With this pilot study we will first focus on a potential factor of influence on PSS practitioners are currently recommended to change in consultation, namely illness perception.
Research question / problem definition
Negative illness perception has been associated with higher levels of PSS and is suggested to be an important perpetuating factor for some children with severe PSS. It is unknown if consultations with pediatricians change these perceptions.
Workplan
For this pilot study, children, parent(s) and/or caregiver(s) referred for PSS to the Martini Hospital Groningen or the UMC Groningen will be asked to fill in a brief questionnaire before the consultation and afterwards. We will also subtract relevant information with regard to patient and symptom characteristics, and follow-up treatment decisions from medical files.
We aim to include 60 pediatric patients in this study. We expect this to take around 12-14 weeks. During this phase data are gathered, the database is build and introduction and method sections can be written. In the final six weeks of the research project the student can focus on analyzing the data and finalizing the results and discussion section.
During the research project, the student will primarily be based at the pediatric department of the Martini Hospital Groningen.
This pilot study of setting up a clinical cohort will also have a follow-up part (at six and twelve months) and will, when proved feasible, be expanded to investigate more potential factors influencing the course of PSS in children, and enriched with a qualitative interview study.
Start of this pilot study: Between sept-nov 2023.
Aimed start of a qualitative interview study is march 2024.
Start of follow-up parts of this pilot study will be around march 2024 and again between September-November 2024.
References
Nederlandse Vereniging Kindergeneeskunde (NVK). Richtlijn somatisch onvoldoende verklaarde lichamelijke klachten (SOLK) bij kinderen [Internet]. 2019 [cited 2023 Mar 6]. Available from: https://www.nvk.nl/themas/kwaliteit/richtlijnen/richtlijn?componentid=6488085&tagtitles=Maag-Darm-Leverziekten%252b(MDL)%2CNeonatologie%2CSociale%252ben%252bPsychosociale%252bkindergeneeskunde
NGH-Richtlijnen. Somatisch onvoldoende verklaarde lichamelijke klachten (SOLK) [Internet]. 2013 [cited 2023 Mar 6]. Available from: https://richtlijnen.nhg.org/standaarden/somatisch-onvoldoende-verklaarde-lichamelijke-klachten-solk
Janssens KA, Klis S, Kingma EM, Oldehinkel AJ, Rosmalen JG. Predictors for persistence of functional somatic symptoms in adolescents. J Pediatr. 2014 Apr;164(4):900-905.e2.