Project details


Management of external ventricular drainage in patients with aneurysmal subarachnoid hemorrhage.

subarachnoid hemorrhage

J.M.C. van Dijk
dr. A.R.E. Potgieser

Nature of the research:
Clinical epidemiological research.

Fields of study:

Background / introduction
Subarachnoid hemorrhage (SAH) is a life-threatening event that causes significant mortality and morbidity. An important complication of the bleeding is hydrocephalus, which can be treated with external ventricular drainage in the acute phase. Previous research from our group showed an increased rebleeding risk of untreated aneurysmal SAH with external ventricular drainage (1). De optimal approach with regard to management and discontinuation of the external ventricular drainage is unknown. Optimization may result in fewer drain-related infections, prevention of a permanent shunt and possibly fewer rebleeds. (2)
Research question / problem definition
What is the optimal approach to management and discontinuation of external ventricular drainage after aneurysmal subarachnoid hemorrhage?
The student will use our SAH database, which contains all aneurysmal SAH’s in the period 1998-2017 to make a survey of management and outcomes of the current strategy towards external ventricular drainage. The student will cooperate in the collection and analysis of the data. When successful, there are many opportunities to continue this line of research in a (MD)PhD project.
1. Prediction of outcome after subarachnoid hemorrhage: timing of clinical assessment. van Donkelaar CE, Bakker NA, Veeger NJ, Uyttenboogaart M, Metzemaekers JD, Eshghi O, Mazuri A, Foumani M, Luijckx GJ, Groen RJ, van Dijk JM. J Neurosurg. 2017 Jan;126(1):52-59.
2. Intermittent CSF drainage and rapid EVD weaning approach after subarachnoid hemorrhage: association with fewer VP shunts and shorter length of stay. Rao SS, Chung DY, Wolcott Z, Sheriff F, Khawaja AM, Lee H, Guanci MM, Leslie-Mazwi TM, Kimberly WT, Patel AB, Rordorf GA. J Neurosurg. 2019 Apr 26:1-6.
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