Project details


Infant development: collecting norm data for two novel assessments

infant development infant assessment developmental disorders

Prof. dr. M. Hadders-Algra
Dr. K.R. Heineman

Nature of the research:
Applied clinical research - assessment of various aspects of infant behaviour

Fields of study:
pediatrics neurology

Background / introduction
Recently two neurodevelopmental assessments have been developed: the Infant Motor Profile (IMP) and the Standardized Infant NeuroDevelopmental Assessment (SINDA). The IMP assesses infant motor behaviour and assists in high risk infants tailor-made physical therapy guidance and prediction of developmental outcome. SINDA assists general paediatricians to detect at early age infants at risk for neurodevelopmental disorders. From January 2017 we start to collect norm data for both assessments. This allows for the investigation of the association between neurological condition (SINDA) and motor development (IMP).
Research question / problem definition
Are specific aspects of neurological condition (e.g., muscle tone, reflexes, cranial nerve function) of infants associated with specific aspects of motor behaviour (e.g., variation and adaptability)?
From January 2017 onwards 1700 infants aged 2 to 18 months will be assessed with the IMP and SINDA. The IMP assesses the quality of spontaneous motor behaviour on the basis of a video-recording of this behaviour. It evaluates motor behaviour in five domains (variation and adaptability, symmetry, fluency and performance). SINDA consists of two subscales: neuromotor condition and development. In addition standardized information on perinatal and social data is collected. Associations between aspects of IMP and SINDA are analysed, and those between perinatal and social characteristics and performance on IMP and SINDA.
Hadders-Algra M. Variation and variability: key words in human motor development. Phys Ther 2010; 90:1823–37.

Heineman KR, Middelburg KJ, Bos AF, Eidhof L, La Bastide-Van Gemert S, Van Den Heuvel ER, Hadders-Algra M. Reliability and concurrent validity of the Infant Motor Profile. Dev Med Child Neurol. 2013;55:539-45.

Heineman KR, Bos AF, Hadders-Algra M. Infant Motor Profile and cerebral palsy: promising associations. Dev Med Child Neurol 2011;53 Suppl 4:40-5.

Heineman KR, La Bastide-Van Gemert S, Fidler V, Middelburg KJ, Bos AF, Hadders-Algra M. Construct validity of the Infant Motor Profile: relation with prenatal, perinatal, and neonatal risk factors. Dev Med Child Neurol 2010;52:e209-15.

Pietz J, Tacke U, Rupp A, Philippi H, Hadders-Algra M. The Standardized Infant NeuroDevelopmental Assessment (SINDA): development of the neuromotor scale. . Dev Med Child Neurol. 2014; 56, suppl 4: 43-44.
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