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Project properties
Title | A comparison of arterial and transcutaneous carbon dioxide as a measure of nocturnal ventilatory efficacy during home mechanical ventilation. |
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Keywords | COPD Non-invasive ventilation respiratory failure |
Researchers |
Prof. dr. M.L. Duiverman T. Raveling |
Nature of the research | Clinical research |
Fields of study | pulmonology intensive care |
Research question / problem definition |
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To determine if CO2 obtained from daytime arterial blood gas a good measure of nocturnal ventilatory efficacy, when compared to nocturnal transcutaneous CO2 measurement. |
Workplan |
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The aim is to compare the PaCO2 and TcCO2 measurements of approximately 100 patients. The data for this research project have been collected during the past years in 2 trials but require to be checked and analysed. As the data are already collected, this project of very well suitable for a masters research project. In the Netherlands, HMV is organised in a unique way as only 4 centers facilitate this treatment. You will participate in our HMV team of the UMCG and the close group of clinical PhD students of the pulmonary department. You will have the opportunity to participate in the outpatient clinics and inpatient initiation on HMV, and are welcome to go on home visits with our specialised nursed. Furthermore, you will get the unique opportunity to learn about HMV, a very specialized area of care. Daily supervision will be by a PhD student and a pulmonologist of the HMV center. The project will lead to a scientific publication in a high ranked journal, which you would be welcome to co-author. Please feel free to contact us for more information. |
References |
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1) Raveling T , Vonk J , Struik FM , Goldstein R , Kerstjens HAM , Wijkstra PJ , Duiverman ML . Chronic non-invasive ventilation for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews TBD, Issue TBD. Art. No.: CD002878. DOI: 10.1002/14651858.CD002878.pub2. 2) Ergan B, Oczkowski S, Rochwerg B,et al. European Respiratory Society guidelines onlong-term home non-invasive ventilation for management of COPD.Eur Respir J 2019; 54: 1901003 3) Conway A, Tipton E, Liu W-H, et al. Thorax 2019;74:157–163. |