List of projects by field of study



Below you see a list of researchprojects within a certain field of study. Please use the selectbox to view researchprojects of another field of research.

It  is also possible to search for keywords.

Click the title of a researchproject for more details.

 

Anti-fibrotische effecten van Verteporfin

Researchers
R.A. Bank
I.J. de Jong
B. Meijer
D.C.J. Mohede

Keywords:
Peyronie disease Verteporfin

Application of Next-Generation Sequencing in managing hospital outbreaks with Multidrug Resistant Gram-Negative Bacteria

Researchers
Prof. dr. A.W. Friedrich

Keywords:
molecular biology molecular microbiology

Assessing the potential of aneuploidy targeting drugs

Researchers
No researchers found

Keywords:
Mouse models Aneuploidy Chromosomal instability

Autophagy as target to reduce sterile inflammation: a potential treatment for auto-immune diseases.

Researchers
prof. F.G.M. Kroese
prof. A. Vissink
prof. H. Bootsma

Keywords:
immunology Autophagy animal models

C/EBPβ-LIP induced cancer cell metabolism

Researchers
Prof. dr. C.F. Calkhoven
T. Ackermann

Keywords:
Cancer cell metabolism nutrient addiction

Calorie mimetic activities of amino acids through regulation of C/EBPβ-LIP translation.

Researchers
Prof. dr. C.F. Calkhoven
M.A. Zaini

Keywords:
cancer metabolism Calorie restriction

Caspase-1 inhibitors to fight neuroinflammation

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
crystallography Alzheimers Caspse 1

CD45RB and tolerance induction: mechanism and preclinical testing

Researchers
prof. dr. S. Poppema

Keywords:
transplantation in vitro tolerance induction

Cellular and organismal ageing and (neuro)degeneration: effects of molecular chaperones

Researchers
prof. dr. H.H. Kampinga
dr. S. Carra

Keywords:
heat shock proteins molecular chaperones protein folding diseases chaperonopathies

Chaperoning DNA repair

Researchers
Dr. S. Bergink

Keywords:
DNA repair genome stability

Characterizing genes that convert aneuploid cells into aneuploid cancer cells

Researchers
No researchers found

Keywords:
Mouse models Aneuploidy Chromosomal instability

Chemical Correction of FVII Mutation

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
hemophilia factor VIII crystallography

Chemical correction of the R175C p53 missmutation

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
p53 missmutation chemical correction novel cancer drug

Chemotherapy-induced cellular senescence

Researchers
Dr. M. Demaria

Keywords:
chemotherapy Cellular senescence Skin cancer

Correlation of clinical characteristics and treatment outcome with genetic alterations (EGFR, KRAS, ALK, BRAF, ROS1 and p53) in NSCLC stage IV.

Researchers
Prof. dr. F. Griesinger

Keywords:
lung cancer molecular biology

Enterovirus evolution and neurotropism

Researchers
Coretta Van Leer Buter
Lilli Gard
Jelte Helfferig
Bert Niesters
Marjolein Knoester

Keywords:
Sequencing respiratory viruses paralysis

Epigenetics of Endothelial Dysfunction

Researchers
dr. G. Krenning
Dr. M.C. Harmsen
M. Maleszewska

Keywords:
epigenetics Endothelial Cell Polycomb

Fragment based drug discovery of antagonists of the Il17-Il17rec. interaction

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
crystallography interleukin small molecule

Functional characterization of genetic susceptibility variants of Celiac disease

Researchers
V. Kumar
dr. S. Withoff
prof. dr. C. Wijmenga

Keywords:
transcription factor celiac disease autoimmune disease EMSA ChIP assay

Gastrointestinal treatment of severe mental disorders (GUTS)

Researchers
Dr. J. Fu
I.E.C. Sommer
B. Haarman
S. El Aidy
N. Festen

Keywords:
severe mental disorders probiotics randomized controlled trial

Genetics of asthma: the role of Protocadherin-1 in airway epithelial integrity and function.

Researchers
M.C. Nawijn

Keywords:
asthma functional genetics bronchial epithelium

Hemagglutinin targeting small molecules as next generation influenza drugs

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
influenza small molecule hemagglutinin

Identification and characterization of novel mTOR regulators

Researchers
prof. dr. K. Thedieck

Keywords:
proteomics Metabolic signaling systems biology

Identification of the gene regulatory processes underlying the pathophysiology of type 2 diabetes.

Researchers
dr. J.W. Jonker

Keywords:
gene regulation energy metabolism type 2 diabetes

Illustrating the role of microbiome in human health

Researchers
Dr. J. Fu
Prof. M.H. Hofker
D.P.Y. Koonen

Keywords:
metabolism bioinformatics metagenomics

Imaging of Cancer Cell Death: pre-clinical development of new probes for quantification of caspase-3 activity and PS exposure

Researchers
prof. dr. S. de Jong
dr. H.H. Boersma
dr. A. Rybczynska
prof. dr. R.A. Dierckx
Prof. dr. P.H. Elsinga

Keywords:
pre-clinical imaging cancer cell apoptosis kinetic modeling

Inducing regeneration through manipulation of Wnt signaling

Researchers
dr. P.M. Weissert
Prof. dr. E.V. Berezikov

Keywords:
stem cells regeneration Wnt signaling

Investigating the role of lincRNAs in autoimmune diseases

Researchers
dr. S. Withoff
V. Kumar
prof. dr. C. Wijmenga

Keywords:
RNA celiac disease autoimmune disease

Investigating the role of miRNAs in autoimmune diseases

Researchers
dr. S. Withoff
V. Kumar
prof. dr. C. Wijmenga

Keywords:
microRNA miRNA celiac disease autoimmune disease non-coding RNA

microRNAs in Diabetic Retinopathy

Researchers
dr. G. Krenning
J.F. Friedrich

Keywords:
microRNA diabetes Endothelial Cell

Mysterious cross-talk: (cross)-linking collagen biosynthesis to cancer

Researchers
Drs. R.A.F. Gjaltema
Prof. dr. R.A. Bank
prof. dr. M.G. Rots

Keywords:
cancer epigenetics fibrosis

Novel miRNA - target gene interactions in B cell lymphoma

Researchers
dr. A. van den Berg
dr. J.L. Kluiver

Keywords:
microRNA B cell lymphoma microRNA target genes

Pathotyping of Streptococus pneumoniae to obtain a better insight in the invasive disease potential of strains.

Researchers
Dr. J.J.E. Bijlsma
K. Elberse

Keywords:
Streptococcus pneumoniae molecular typing genome analysis

Protein damage control in diseases of aging

Researchers
No researchers found

Keywords:
protein aggregation C. elegans Parkinson's disease Alzheimer's disease Huntington's disease

Regulation of aging and age-related disease by transcription factors, chromatin states, and the epigenome

Researchers
dr. C.G. Riedel

Keywords:
epigenetics transcriptional regulation aging

Role of Fibroblast growth factor 1 (FGF1) in the development en therapy of type 2 diabetes

Researchers
dr. J.W. Jonker

Keywords:
obesity energy metabolism type 2 diabetes

Role of the small heat shock protein HspB8 in protein folding diseases and implication in peripheral neuropathies

Researchers
prof. dr. H.H. Kampinga
dr. S. Carra

Keywords:
Axonal transport vesicular trafficking molecular chaperones protein aggregation Autophagy

Small molecules for the cancer relevant protein protein interaction p53 mdm2

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
crystallography protein protein interaction small molecule inhibitor

Stem cells and oncogenesis in a novel model organism

Researchers
Prof. dr. E.V. Berezikov
dr. D. Olivieri

Keywords:
cancer stem cells DNA damage response

Stem cells in heart failure research: generating an in vitro disease model.

Researchers
M.F.G.A. Hoes

Keywords:
stem cells cardiac differentiation iPSC

The regulation of stem cell decisions in developing and ageing tissues.

Researchers
Dr. J.T.M.L. Paridaen

Keywords:
development Stem cell division zebrafish

The role of aneuploidy in ageing

Researchers
No researchers found

Keywords:
Mouse models Aneuploidy Chromosomal instability

The role of noncoding RNAs in B cell lymphoma

Researchers
dr. A. van den Berg
dr. J.L. Kluiver

Keywords:
Long non-coding RNAs miRNAs Regulating networks

The role of phospholipid flippases in autophagy

Researchers
Dr. F. Kriegenburg
Prof. dr. F.M. Reggiori

Keywords:
Autophagy lipid flippases Ymr1

The role of the cargo during the induction of selective autophagy

Researchers
Prof. dr. F.M. Reggiori
dr. R. Gómez-Sánchez

Keywords:
Autophagy Yeast Cvt pathway

Towards a treatment of the autoimmune disease thrombotic thrombocytopenic purpura.

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
thrombotic thrombocytopenic purpura ADAMTS13 drug discovery

Unraveling disease mechanisms in Noordzeeziekte (progressive myoclonus epilepsy due to GOSR2 mutations)

Researchers
prof. dr. O.C.M. Sibon
prof. dr. M.A.J. de Koning-Tijssen
dr. T.J. de Koning
Dr. D.S. Verbeek
dr. A.J.A. van de Sluis

Keywords:
Noordzeeziekte basic research disease models

Unraveling the causative genes – and pathways - for autoimmune diseases

Researchers
V. Kumar
dr. S. Withoff
prof. dr. C. Wijmenga

Keywords:
pathway analysis celiac disease autoimmune disease gene enrichment T cell genes

Unraveling the genetic and biological pathways of spinocerebellar ataxia

Researchers
Dr. D.S. Verbeek

Keywords:
neurodegeneration exome sequencing human genetics

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