List of projects by field of study



Below you see a list of researchprojects within a certain field of study. Please use the selectbox to view researchprojects of another field of research.

It  is also possible to search for keywords.

Click the title of a researchproject for more details.

 

A new probe to study cancer cells: From dynamics to nanometer-localization

Researchers
M.A. de Beer

Keywords:
Advanced Microscopy cancer cells engineering

A protein restoration therapy for the treatment of Microvillus Inclusion Disease

Researchers
No researchers found

Keywords:
intestinal disorder protein restoration therapy diagnostic test

A three-dimensional cell culture system for the study of intestinal epithelial integrity

Researchers
Dr. S.C.D. van IJzendoorn

Keywords:
intestinal integrity epithelial cells Advanced cell culture

Assessing the potential of aneuploidy targeting drugs

Researchers
No researchers found

Keywords:
Mouse models Aneuploidy Chromosomal instability

C/EBPβ-LIP induced cancer cell metabolism

Researchers
Prof. dr. C.F. Calkhoven
T. Ackermann

Keywords:
Cancer cell metabolism nutrient addiction

Calorie mimetic activities of amino acids through regulation of C/EBPβ-LIP translation.

Researchers
Prof. dr. C.F. Calkhoven
M.A. Zaini

Keywords:
cancer metabolism Calorie restriction

Cellular and organismal ageing and (neuro)degeneration: effects of molecular chaperones

Researchers
prof. dr. H.H. Kampinga
dr. S. Carra

Keywords:
heat shock proteins molecular chaperones protein folding diseases chaperonopathies

Chaperoning DNA repair

Researchers
Dr. S. Bergink

Keywords:
DNA repair genome stability

Characterizing genes that convert aneuploid cells into aneuploid cancer cells

Researchers
No researchers found

Keywords:
Mouse models Aneuploidy Chromosomal instability

Chemotherapy-induced cellular senescence

Researchers
Dr. M. Demaria

Keywords:
chemotherapy Cellular senescence Skin cancer

Drosophila as model organism for neurodegeneration and aging

Researchers
prof. dr. O.C.M. Sibon

Keywords:
ageing neurodegenerative diseases Drosophila

Drug Delivery across the Blood-Brain Barrier

Researchers
dr. I.S. Zuhorn

Keywords:
drug delivery blood-brain barrier

Epithelial cells alarming the immune system in COPD

Researchers
dr. D.J. Slebos
prof. dr. A.J.M. van Oosterhout

Keywords:
immune response COPD danger signals

Functional characterization of genetic susceptibility variants of Celiac disease

Researchers
V. Kumar
dr. S. Withoff
prof. dr. C. Wijmenga

Keywords:
transcription factor celiac disease autoimmune disease EMSA ChIP assay

Hemagglutinin targeting small molecules as next generation influenza drugs

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
influenza small molecule hemagglutinin

Hibernation: the natural model of safeguarding organs from damage Winterslaap: het natuurlijke model om organen tegen schade te wapenen

Researchers
Prof. dr. R.H. Henning

Keywords:
transplantation Hibernation organ preservation

HMGB1 als potentiële sleutel tot ontsteking in het syndroom van Sjögren.

Researchers
prof. F.G.M. Kroese
dr. J. Westra

Keywords:
inflammation pharmacology connective tissue disease

How do tumor cells survive genomic instability?

Researchers
dr. M.A.T.M. van Vugt
Dr. R.S.N. Fehrmann

Keywords:
breast cancer genomic instability bio-informatics

Hydrogen Sulfide in Biology and Disease

Researchers
dr. H.G.D. Leuvenink
Prof. dr. H. van Goor
Prof. dr. J.L. Hillebrands

Keywords:
hydrogen sulfide renal disease transplantatation

Identification and characterization of novel mTOR regulators

Researchers
prof. dr. K. Thedieck

Keywords:
proteomics Metabolic signaling systems biology

Identification of the gene regulatory processes underlying the pathophysiology of type 2 diabetes.

Researchers
dr. J.W. Jonker

Keywords:
gene regulation energy metabolism type 2 diabetes

Inducing regeneration through manipulation of Wnt signaling

Researchers
dr. P.M. Weissert
Prof. dr. E.V. Berezikov

Keywords:
stem cells regeneration Wnt signaling

Interactions between CNS and immune system in neurodegenerative diseases.

Researchers
P.F. Dijkers

Keywords:
Drosophila Alzheimer's disease Genetic screens

Intestinal wall permeability in de novo Parkinson’s Disease

Researchers
prof. dr. T. van Laar
JM Boertien

Keywords:
Parkinson's disease translational Intestinal wall permeability

Intracellulaire transportproblemen in genetische afwijkingen

Researchers
Dr. S.C.D. van IJzendoorn

Keywords:
metabolism epithelial disorders

Involvement of the immune system in neurodegerative diseases

Researchers
P.F. Dijkers

Keywords:
immunology neurodegeneration

Isolation, characterisation and activation of human renal endothelial cells after postmortal kidney donation

Researchers
Dr. J. van den Born
Prof. dr. S.P. Berger
R. Lammerts

Keywords:
kidney transplantation endothelial cells complement

Leidt infectie met rotavirus of cytomegalievirus tot hedgehogactivatie en epitheliale naar mesenchymale transitie in de cholangiocyt?

Researchers
H. Hoekstra
R.C. Lind
dr. J.B.F. Hulscher

Keywords:
immune response biliary atresia cholangiocyte

Liver syndecan-1 shedding and dyslipidaemia in renal diseases

Researchers
Dr. J. van den Born
S. Adepu

Keywords:
cardiovascular kidney triglyceride

Long non-coding RNA in liver disease

Researchers
dr. A.J.A. van de Sluis
Dr. J. Fu
Prof. M.H. Hofker

Keywords:
genomics molecular genetics cardiometabolic risk

Loss of cell-cell contacts leads to congenital diarrhea

Researchers
dr. B.N.G. Giepmans
dr. U. Schnell

Keywords:
signalling growth control cell-cell junction microscopy

Novel miRNA - target gene interactions in B cell lymphoma

Researchers
dr. A. van den Berg
dr. J.L. Kluiver

Keywords:
microRNA B cell lymphoma microRNA target genes

Nuclear Envelope deformation in Ageing

Researchers
dr. L.M. Veenhoff

Keywords:
Ageing, Nuclear Envelope, Nuclear Pore Complex

Onderzoek naar versnelde veroudering door chemotherapie bij patiënten met zaadbalkanker

Researchers
prof. dr. JA Gietema
drs ELD Volders

Keywords:
chemotherapy aging testicular cancer

Protein damage control in diseases of aging

Researchers
No researchers found

Keywords:
protein aggregation C. elegans Parkinson's disease Alzheimer's disease Huntington's disease

Regeneration of myelin in multiple sclerosis lesions

Researchers
prof.dr. D. Hoekstra

Keywords:
multiple sclerosis oligodendrocytes assembly of myelin membranes

Regulation of aging and age-related disease by transcription factors, chromatin states, and the epigenome

Researchers
dr. C.G. Riedel

Keywords:
epigenetics transcriptional regulation aging

Role of the small heat shock protein HspB8 in protein folding diseases and implication in peripheral neuropathies

Researchers
prof. dr. H.H. Kampinga
dr. S. Carra

Keywords:
Axonal transport vesicular trafficking molecular chaperones protein aggregation Autophagy

Schade herstellen in multiple sclerosis

Researchers
dr. W. Baron

Keywords:
oligodendrocytes myelin multiple sclerosis

Small molecules for the cancer relevant protein protein interaction p53 mdm2

Researchers
prof.dr. A.S.S. Doemling
dr. M.R. Groves

Keywords:
crystallography protein protein interaction small molecule inhibitor

Stem cells and oncogenesis in a novel model organism

Researchers
Prof. dr. E.V. Berezikov
dr. D. Olivieri

Keywords:
cancer stem cells DNA damage response

The dual hit hypothesis of schizophrenia.

Researchers
dr. E.F.J. de Vries
dr. J. Doorduin
C. Guerrin

Keywords:
stress inflammation schizophrenia

The effect of human cytomegalovirus-encoded viral chemokine receptors on renal fibrogenesis in renal transplantation

Researchers
Dr. J. van den Born
prof. dr. W.J. van Son

Keywords:
virus kidney transplantation fibrosis

The pathophysiological changes in mitochondrial function associated with organ donation

Researchers
Dr. M.E. Erasmus
R.A. Reblledo
C.M.V. Hottenrott

Keywords:
transplantation physiology mitochondria

The regulation of stem cell decisions in developing and ageing tissues.

Researchers
Dr. J.T.M.L. Paridaen

Keywords:
development Stem cell division zebrafish

The role of aneuploidy in ageing

Researchers
No researchers found

Keywords:
Mouse models Aneuploidy Chromosomal instability

The role of phospholipid flippases in autophagy

Researchers
Dr. F. Kriegenburg
Prof. dr. F.M. Reggiori

Keywords:
Autophagy lipid flippases Ymr1

The role of the cargo during the induction of selective autophagy

Researchers
Prof. dr. F.M. Reggiori
dr. R. Gómez-Sánchez

Keywords:
Autophagy Yeast Cvt pathway

Therapeutic blockade of lymphangiogenesis in renal diseases

Researchers
Dr. J. van den Born

Keywords:
inflammation fibrosis angiogenesis

To study the loss of epithelial barrier function in human cholangiocytes in various perfusion solutions.

Researchers
Dr. S.C.D. van IJzendoorn
Prof. dr. R.J. Porte
drs. A.C. Westerkamp

Keywords:
liver transplantation ischemia/reperfusion injury preservation fluids

Type 1 diabetes-induced alterations in islets of Langerhans

Researchers
dr. B.N.G. Giepmans
P. de Boer

Keywords:
Advanced Microscopy beta cell destruction insulitis

Understanding the pathogenesis of microvillus inclusion disease

Researchers
Dr. S.C.D. van IJzendoorn

Keywords:
intestinal disease cellular architecture microvillus inclusion disease

Understanding the pathophysiology in malnutrition: Improving the outcome of malnourished children.

Researchers
Dr. P.F. van Rheenen
B.M. Bakker

Keywords:
global child health translational

Understanding the role of fibulin-1 in the ECM niche in Idiopathic Pulmonary Fibrosis

Researchers
dr. B.N. Melgert
J.K. Burgess
R.A. Bank

Keywords:
fibrosis extracellular matrix

Unraveling the genetic and biological pathways of spinocerebellar ataxia

Researchers
Dr. D.S. Verbeek

Keywords:
neurodegeneration exome sequencing human genetics

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