List of projects by field of study

Below you see a list of researchprojects within a certain field of study. Please use the selectbox to view researchprojects of another field of research.

It is also possible to search for keywords.

Click the title of a researchproject for more details.

Assessing the potential of aneuploidy targeting drugs
Researchers No researchers found
Keywords: Mouse models Aneuploidy Chromosomal instability

Cancer Immunotherapy
Researchers No researchers found
Keywords: immunotherapy viral vector cancer vaccine

Characterizing genes that convert aneuploid cells into aneuploid cancer cells
Researchers No researchers found
Keywords: Mouse models Aneuploidy Chromosomal instability

Chemical correction of the R175C p53 missmutation
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: p53 missmutation chemical correction novel cancer drug

Chemotherapy-induced cellular senescence
Researchers Dr. M. Demaria
Keywords: chemotherapy Cellular senescence Skin cancer

Clonal tracking in the hematopoietic system
Researchers Prof. dr. G. de Haan Dr. L. Bystrykh
Keywords: stem cells transduction mutagenesis

COPZ1:COPgamma interaction as a target for the treatment of metastatic and dormant cancers in humans
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: cancer Structural biology Non-metastatic

Epigenetic edeting
Researchers D. Goubert
Keywords: breast cancer epigenetics CRISP/Cas

Epigenetic regulation in the hematopoietic system
Researchers Prof. dr. G. de Haan Dr. L. Bystrykh
Keywords: epigenetics hematopoiesis stem cells polycomb group proteins

Esophageal cancer stem cells: validation and characterization of cFOS and KLF2 genes in maintaining stem cell properties in esophageal cancer.
Researchers prof.dr. F.A.E. Kruyt
Keywords: cancer cancer stem cells oncology

Fragment based drug discovery of antagonists of the Il17-Il17rec. interaction
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: crystallography interleukin small molecule

How do tumor cells survive genomic instability?
Researchers dr. M.A.T.M. van Vugt Dr. R.S.N. Fehrmann
Keywords: breast cancer genomic instability bio-informatics

How do tumors with a DNA repair defect survive their genomic instability?
Researchers dr. M.A.T.M. van Vugt
Keywords: cell cycle BRCA1 DNA repair

Identifying human hematopoietic stem cell-niche interactions in relation to self-renewal and quiescence
Researchers prof. dr. J.J. Schuringa
Keywords: leukemia hematopoiesis human hematopoietic stem cells

Imaging of Cancer Cell Death: pre-clinical development of new probes for quantification of caspase-3 activity and PS exposure
Researchers prof. dr. S. de Jong dr. H.H. Boersma dr. A. Rybczynska prof. dr. R.A. Dierckx Prof. dr. P.H. Elsinga
Keywords: pre-clinical imaging cancer cell apoptosis kinetic modeling

Investigating the mechanisms of anticancer metal-compounds transport and accumulation in cancer cells
Researchers Dr. A. Casini Prof. dr. G.M.M. Groothuis
Keywords: platinum anticancer compounds drug transporters mechanisms of action

Menin:MLL interactions as a target for the treatment of acute leukemia
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: leukemia Structural biology Drug design

Molecular mechanisms involved in BCR-ABL/BMI1 induced self-renewal of leukemic stem cells
Researchers prof. dr. J.J. Schuringa
Keywords: hematopoiesis leukemic stem cells self-renewal human hematopoietic stem cells

Molecular mechanisms involved self-renewal of leukemic stem cells from AML patients
Researchers prof. dr. J.J. Schuringa prof.dr. E. Vellenga
Keywords: hematopoiesis leukemic stem cells self-renewal human hematopoietic stem cells

Novel miRNA - target gene interactions in B cell lymphoma
Researchers dr. A. van den Berg dr. J.L. Kluiver
Keywords: microRNA B cell lymphoma microRNA target genes

Role of anesthetic and analgesic techniques in long-term survival after laparoscopic surgery for colon cancer
Researchers Dr. D.J. Bosch Prof. dr. M.M.R.F. Struys
Keywords: anesthesia

Sigma Receptor Ligands: Possible Applications as Anti-Tumor Agents and as Radiopharmaceuticals
Researchers dr. A. Rybczynska A. van Waarde Prof. dr. P.H. Elsinga dr. W. Helfrich prof. dr. R.A. Dierckx
Keywords: cell death cell cycle multidrug resistance

Small molecules for the cancer relevant protein protein interaction p53 mdm2
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: crystallography protein protein interaction small molecule inhibitor

Stem cells and oncogenesis in a novel model organism
Researchers Prof. dr. E.V. Berezikov dr. D. Olivieri
Keywords: cancer stem cells DNA damage response

Targeting homing and activity of immune effector cells to tumors – a step forward in cancer immunotherapy (preferred period 2014/2015)
Researchers Dr. O. Draghiciu prof. dr. H.W. Nijman Prof. dr. C.A.H.H. Daemen
Keywords: viral vector immunotherapy

The effect of O-glycosylation of Death Receptor 4 and 5 on TRAIL sensitivity
Researchers prof. dr. W.J. Quax I.A.M. van Roosmalen MSc. D. Wilffert
Keywords: O-glycosylation cancer cell apoptosis TRAIL Death Receptors

The role of aneuploidy in ageing
Researchers No researchers found
Keywords: Mouse models Aneuploidy Chromosomal instability

The role of cAMP and WNT signaling in the development of neuroblastoma
Researchers Dr. R. Gosens
Keywords: WNT neuroblastoma cAMP

The role of noncoding RNAs in B cell lymphoma
Researchers dr. A. van den Berg dr. J.L. Kluiver
Keywords: Long non-coding RNAs miRNAs Regulating networks

The role of Nrf2 in ovarian carcinogenesis
Researchers prof. dr. M.G. Rots
Keywords: carcinogenesis gene expression oxidative stress

Unraveling the non-coding RNA network involved in IGF signaling
Researchers dr. A. van den Berg dr. J.L. Kluiver dr. L. Visser
Keywords: non-coding RNA B-cell lymphoma IGF signaling

What is the impact of follow-up MRI scans on treatment decisions in patients with a glioblastoma?
Researchers prof. dr. R.A. Dierckx dr. A van der Hoorn dr. P.J. van Laar dr. R.H. Enting
Keywords: imaging neurology Glioblastoma

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