Projectenlijst per vakgebied

Hieronder ziet u een lijst van projecten behorende tot een bepaald vakgebied. Gebruik de bovenstaande keuzelijst om projecten van een ander vakgebied te tonen.

Het is ook mogelijk om te zoeken op trefwoord.

Klik op de titel van het project voor meer informatie.

Assessing the potential of aneuploidy targeting drugs
Researchers No researchers found
Keywords: Mouse models Aneuploidy Chromosomal instability

Cancer Immunotherapy
Researchers No researchers found
Keywords: immunotherapy viral vector cancer vaccine

Characterizing genes that convert aneuploid cells into aneuploid cancer cells
Researchers No researchers found
Keywords: Mouse models Aneuploidy Chromosomal instability

Chemical correction of the R175C p53 missmutation
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: p53 missmutation chemical correction novel cancer drug

Chemotherapy-induced cellular senescence
Researchers Dr. M. Demaria
Keywords: chemotherapy Cellular senescence Skin cancer

Clonal tracking in the hematopoietic system
Researchers Prof. dr. G. de Haan Dr. L. Bystrykh
Keywords: stem cells transduction mutagenesis

COPZ1:COPgamma interaction as a target for the treatment of metastatic and dormant cancers in humans
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: cancer Structural biology Non-metastatic

Epigenetic edeting
Researchers D. Goubert
Keywords: breast cancer epigenetics CRISP/Cas

Epigenetic regulation in the hematopoietic system
Researchers Prof. dr. G. de Haan Dr. L. Bystrykh
Keywords: epigenetics hematopoiesis stem cells polycomb group proteins

Esophageal cancer stem cells: validation and characterization of cFOS and KLF2 genes in maintaining stem cell properties in esophageal cancer.
Researchers prof.dr. F.A.E. Kruyt
Keywords: cancer cancer stem cells oncology

Fragment based drug discovery of antagonists of the Il17-Il17rec. interaction
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: crystallography interleukin small molecule

How do tumor cells survive genomic instability?
Researchers dr. M.A.T.M. van Vugt Dr. R.S.N. Fehrmann
Keywords: breast cancer genomic instability bio-informatics

How do tumors with a DNA repair defect survive their genomic instability?
Researchers dr. M.A.T.M. van Vugt
Keywords: cell cycle BRCA1 DNA repair

Identifying human hematopoietic stem cell-niche interactions in relation to self-renewal and quiescence
Researchers prof. dr. J.J. Schuringa
Keywords: leukemia hematopoiesis human hematopoietic stem cells

Imaging of Cancer Cell Death: pre-clinical development of new probes for quantification of caspase-3 activity and PS exposure
Researchers prof. dr. S. de Jong dr. H.H. Boersma dr. A. Rybczynska prof. dr. R.A. Dierckx Prof. dr. P.H. Elsinga
Keywords: pre-clinical imaging cancer cell apoptosis kinetic modeling

Investigating the mechanisms of anticancer metal-compounds transport and accumulation in cancer cells
Researchers Dr. A. Casini Prof. dr. G.M.M. Groothuis
Keywords: platinum anticancer compounds drug transporters mechanisms of action

Menin:MLL interactions as a target for the treatment of acute leukemia
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: leukemia Structural biology Drug design

Molecular mechanisms involved in BCR-ABL/BMI1 induced self-renewal of leukemic stem cells
Researchers prof. dr. J.J. Schuringa
Keywords: hematopoiesis leukemic stem cells self-renewal human hematopoietic stem cells

Molecular mechanisms involved self-renewal of leukemic stem cells from AML patients
Researchers prof. dr. J.J. Schuringa prof.dr. E. Vellenga
Keywords: hematopoiesis leukemic stem cells self-renewal human hematopoietic stem cells

Novel miRNA - target gene interactions in B cell lymphoma
Researchers dr. A. van den Berg dr. J.L. Kluiver
Keywords: microRNA B cell lymphoma microRNA target genes

Role of anesthetic and analgesic techniques in long-term survival after laparoscopic surgery for colon cancer
Researchers Dr. D.J. Bosch Prof. dr. M.M.R.F. Struys
Keywords: anesthesia

Sigma Receptor Ligands: Possible Applications as Anti-Tumor Agents and as Radiopharmaceuticals
Researchers dr. A. Rybczynska A. van Waarde Prof. dr. P.H. Elsinga dr. W. Helfrich prof. dr. R.A. Dierckx
Keywords: cell death cell cycle multidrug resistance

Small molecules for the cancer relevant protein protein interaction p53 mdm2
Researchers prof.dr. A.S.S. Doemling dr. M.R. Groves
Keywords: crystallography protein protein interaction small molecule inhibitor

Stem cells and oncogenesis in a novel model organism
Researchers Prof. dr. E.V. Berezikov dr. D. Olivieri
Keywords: cancer stem cells DNA damage response

Targeting homing and activity of immune effector cells to tumors – a step forward in cancer immunotherapy (preferred period 2014/2015)
Researchers Dr. O. Draghiciu prof. dr. H.W. Nijman Prof. dr. C.A.H.H. Daemen
Keywords: viral vector immunotherapy

The effect of O-glycosylation of Death Receptor 4 and 5 on TRAIL sensitivity
Researchers prof. dr. W.J. Quax I.A.M. van Roosmalen MSc. D. Wilffert
Keywords: O-glycosylation cancer cell apoptosis TRAIL Death Receptors

The role of aneuploidy in ageing
Researchers No researchers found
Keywords: Mouse models Aneuploidy Chromosomal instability

The role of cAMP and WNT signaling in the development of neuroblastoma
Researchers Dr. R. Gosens
Keywords: WNT neuroblastoma cAMP

The role of noncoding RNAs in B cell lymphoma
Researchers dr. A. van den Berg dr. J.L. Kluiver
Keywords: Long non-coding RNAs miRNAs Regulating networks

The role of Nrf2 in ovarian carcinogenesis
Researchers prof. dr. M.G. Rots
Keywords: carcinogenesis gene expression oxidative stress

Unraveling the non-coding RNA network involved in IGF signaling
Researchers dr. A. van den Berg dr. J.L. Kluiver dr. L. Visser
Keywords: non-coding RNA B-cell lymphoma IGF signaling

What is the impact of follow-up MRI scans on treatment decisions in patients with a glioblastoma?
Researchers prof. dr. R.A. Dierckx dr. A van der Hoorn dr. P.J. van Laar dr. R.H. Enting
Keywords: imaging neurology Glioblastoma

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