List of projects by field of study
Below you see a list of researchprojects within a certain field of study. Please use the selectbox to view researchprojects of another field of research.
It is also possible to search for keywords.
Click the title of a researchproject for more details.
| Abnormal tissue repair and remodeling in COPD; from genomics to biological function |
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| Airway epithelial-to-mesenchymal transition: Compartmentalized cyclic AMP signaling? |
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| Application of Next-Generation Sequencing in managing hospital outbreaks with Multidrug Resistant Gram-Negative Bacteria |
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| Aquaglyceroporin-3 (AQP3) as an “elusive” drug target for cancer treatment: development of new approaches to study its structure and function |
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| Assessing the potential of aneuploidy targeting drugs |
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| Cardiomyopathies due to mutations in Heat Shock Protein |
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| Caspase-1 inhibitors to fight neuroinflammation |
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| Cause and Effect: Genetic susceptibility to noxious particles and the influence of these factors on chromosomal stability |
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| Cellular and organismal ageing and (neuro)degeneration: effects of molecular chaperones |
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| Chaperoning DNA repair |
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| Characterizing genes that convert aneuploid cells into aneuploid cancer cells |
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| Chemical Correction of FVII Mutation |
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| Chemical correction of the R175C p53 missmutation |
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| Chemotherapy-induced cellular senescence |
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| COPZ1:COPgamma interaction as a target for the treatment of metastatic and dormant cancers in humans |
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| Defining the molecular mechanisms for high-frequency transmission of the Staphylococcus aureus USA300 lineage |
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| Development of new chemotherapeutic compounds targeted at histone acetyl transferases |
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| Dissecting the role of cellular senescence in the pathogenesis of COPD |
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| DNA damage and protein quality control (no place available in 2013/14) |
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| Eat more molecular! Modulating the gastrointestinal immune system to support health |
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| Elucidate DNA damage signaling pathway in experimental and human atrial fibrillation |
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| Endothelial-Mesenchymal Transition in Cardiovascular Disease |
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| Epigenetic edeting |
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| Epigenetic editing towards directed gene silencing of oncogenes |
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| Epigenetics of Endothelial Dysfunction |
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| Fibulin-5; a key player in elastogenesis and emphysema development in COPD? |
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| Fragment based drug discovery of antagonists of the Il17-Il17rec. interaction |
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| Functional characterization of genetic susceptibility variants of Celiac disease |
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| Genome instability and neurodegeneration |
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| Hemagglutinin targeting small molecules as next generation influenza drugs |
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| Identification and characterization of novel mTOR regulators |
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| Identification of the gene regulatory processes underlying the pathophysiology of type 2 diabetes. |
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| IL-17A receptor inhibitors for the treatment of inflammation |
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| Illustrating the role of microbiome in human health |
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| Imaging of Cancer Cell Death: pre-clinical development of new probes for quantification of caspase-3 activity and PS exposure |
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| Inducing regeneration through manipulation of Wnt signaling |
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| Investigating the role of lincRNAs in autoimmune diseases |
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| Investigating the role of miRNAs in autoimmune diseases |
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| Keeping inflammation under control: new insights in the NF-kB signaling pathway at the organismal level |
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| Menin:MLL interactions as a target for the treatment of acute leukemia |
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| microRNAs in Diabetic Retinopathy |
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| Novel miRNA - target gene interactions in B cell lymphoma |
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| Optogenetic and chemogenetic approach to tackle neuronal cell death |
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| Protein damage control in diseases of aging |
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| Regulation of aging and age-related disease by transcription factors, chromatin states, and the epigenome |
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| Reversal of cardiomyocyte remodeling in Atrial Fibrillation |
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| Small molecules for the cancer relevant protein protein interaction p53 mdm2 |
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| Sorting membrane proteins: understanding the role of a novel dynamic protein-network in intracellular cargo transport and delivery |
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| Stem cells and oncogenesis in a novel model organism |
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| Telomeres, Genome Integrity, and Replicative Ageing |
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| The effect of O-glycosylation of Death Receptor 4 and 5 on TRAIL sensitivity |
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| The Epac1 and Epac2 signalosome – unravelling molecular mechanisms underlying unwanted effects of β2-agonists with focus on biased signaling |
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| The functionale relevance of microRNAs in COPD; their role in regulating pulmonary fibroblast function in COPD development |
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| The role of aneuploidy in ageing |
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| The role of noncoding RNAs in B cell lymphoma |
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| The role of Nrf2 in ovarian carcinogenesis |
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| The role of p53 in Atrial Fibrillation |
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| The role of phospholipid flippases in autophagy |
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| The role of the cargo during the induction of selective autophagy |
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| Unraveling disease mechanisms in Noordzeeziekte (progressive myoclonus epilepsy due to GOSR2 mutations) |
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| Unraveling the causative genes – and pathways - for autoimmune diseases |
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| Unraveling the genetic and biological pathways of spinocerebellar ataxia |
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| Unraveling the non-coding RNA network involved in IGF signaling |
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