Projectenlijst per vakgebied
Hieronder ziet u een lijst van projecten behorende tot een bepaald vakgebied. Gebruik de bovenstaande keuzelijst om projecten van een ander vakgebied te tonen.
Het is ook mogelijk om te zoeken op trefwoord.
Klik op de titel van het project voor meer informatie.
Abnormal tissue repair and remodeling in COPD; from genomics to biological function |
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Airway epithelial-to-mesenchymal transition: Compartmentalized cyclic AMP signaling? |
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Application of Next-Generation Sequencing in managing hospital outbreaks with Multidrug Resistant Gram-Negative Bacteria |
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Aquaglyceroporin-3 (AQP3) as an “elusive” drug target for cancer treatment: development of new approaches to study its structure and function |
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Assessing the potential of aneuploidy targeting drugs |
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Cardiomyopathies due to mutations in Heat Shock Protein |
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Caspase-1 inhibitors to fight neuroinflammation |
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Cause and Effect: Genetic susceptibility to noxious particles and the influence of these factors on chromosomal stability |
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Cellular and organismal ageing and (neuro)degeneration: effects of molecular chaperones |
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Chaperoning DNA repair |
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Characterizing genes that convert aneuploid cells into aneuploid cancer cells |
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Chemical Correction of FVII Mutation |
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Chemical correction of the R175C p53 missmutation |
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Chemotherapy-induced cellular senescence |
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COPZ1:COPgamma interaction as a target for the treatment of metastatic and dormant cancers in humans |
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Defining the molecular mechanisms for high-frequency transmission of the Staphylococcus aureus USA300 lineage |
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Development of new chemotherapeutic compounds targeted at histone acetyl transferases |
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Dissecting the role of cellular senescence in the pathogenesis of COPD |
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DNA damage and protein quality control (no place available in 2013/14) |
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Eat more molecular! Modulating the gastrointestinal immune system to support health |
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Elucidate DNA damage signaling pathway in experimental and human atrial fibrillation |
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Endothelial-Mesenchymal Transition in Cardiovascular Disease |
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Epigenetic edeting |
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Epigenetic editing towards directed gene silencing of oncogenes |
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Epigenetics of Endothelial Dysfunction |
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Fibulin-5; a key player in elastogenesis and emphysema development in COPD? |
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Fragment based drug discovery of antagonists of the Il17-Il17rec. interaction |
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Functional characterization of genetic susceptibility variants of Celiac disease |
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Genome instability and neurodegeneration |
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Hemagglutinin targeting small molecules as next generation influenza drugs |
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Identification and characterization of novel mTOR regulators |
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Identification of the gene regulatory processes underlying the pathophysiology of type 2 diabetes. |
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IL-17A receptor inhibitors for the treatment of inflammation |
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Illustrating the role of microbiome in human health |
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Imaging of Cancer Cell Death: pre-clinical development of new probes for quantification of caspase-3 activity and PS exposure |
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Inducing regeneration through manipulation of Wnt signaling |
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Investigating the role of lincRNAs in autoimmune diseases |
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Investigating the role of miRNAs in autoimmune diseases |
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Keeping inflammation under control: new insights in the NF-kB signaling pathway at the organismal level |
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Menin:MLL interactions as a target for the treatment of acute leukemia |
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microRNAs in Diabetic Retinopathy |
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Novel miRNA - target gene interactions in B cell lymphoma |
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Optogenetic and chemogenetic approach to tackle neuronal cell death |
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Protein damage control in diseases of aging |
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Regulation of aging and age-related disease by transcription factors, chromatin states, and the epigenome |
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Reversal of cardiomyocyte remodeling in Atrial Fibrillation |
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Small molecules for the cancer relevant protein protein interaction p53 mdm2 |
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Sorting membrane proteins: understanding the role of a novel dynamic protein-network in intracellular cargo transport and delivery |
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Stem cells and oncogenesis in a novel model organism |
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Telomeres, Genome Integrity, and Replicative Ageing |
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The effect of O-glycosylation of Death Receptor 4 and 5 on TRAIL sensitivity |
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The Epac1 and Epac2 signalosome – unravelling molecular mechanisms underlying unwanted effects of β2-agonists with focus on biased signaling |
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The functionale relevance of microRNAs in COPD; their role in regulating pulmonary fibroblast function in COPD development |
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The role of aneuploidy in ageing |
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The role of noncoding RNAs in B cell lymphoma |
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The role of Nrf2 in ovarian carcinogenesis |
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The role of p53 in Atrial Fibrillation |
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The role of phospholipid flippases in autophagy |
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The role of the cargo during the induction of selective autophagy |
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Unraveling disease mechanisms in Noordzeeziekte (progressive myoclonus epilepsy due to GOSR2 mutations) |
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Unraveling the causative genes – and pathways - for autoimmune diseases |
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Unraveling the genetic and biological pathways of spinocerebellar ataxia |
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Unraveling the non-coding RNA network involved in IGF signaling |
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